Serving the business community since 1904, MCCI was excellently steered by eminent business personalities like Mr. M. M. Ispahani, Mr. M. H. Adamjee, Mr. Y. A. Bawany, Mr. Samson H. Chowdhury and many more who are still carrying the flag mast of MCCI. All the names of the former presidents of the Chamber could not be retrieved from the old documents. However, the list of presidents since 1951 is provided below to remember their wonderful contribution towards the society.
| Year | Name of Presidents | Company Name |
| 1949 | Mr. D.P. Fafalios | Ralli Brothers Ltd. |
| 1950 | Mr. A.C. Baxter | — |
| 1951 | Mr. C.E.C. Guthrie | LGN & S.N.G. Ltd. |
| 1952 | Mr. A.R. Faridi | — |
| 1953 | Mr. R.W.N. Ferguson | — |
| 1954 | Mr. A. Jalil | — |
| 1955 | Mr. M. M. Ispahani | M. M. Ispahani Limited |
| 1956 | Mr. M. M. Ispahani | M. M. Ispahani Limited |
| 1957 | Mr. A. A. Khalon | The Pakbay Co. Ltd |
| 1958 | Mr. W. R. Longwill | James Finlay & Co. Ltd |
| 1959 | Mr. M. Naser-ud-Deen Khan | Burmah-Shell Oil Storage and Distributing Co. of Pakistan Ltd. |
| 1960 | Mr. M. M. Ispahani | M. M. Ispahani Limited |
| 1961 | Mr. A. A. Khalon | The Pakbay Co. Ltd |
| 1962 | Mr. A. Ahad | Orr, Dignam & Co. |
| 1963 | Mr. M. H. Adamjee | Adamjee Jute Mills Ltd. |
| 1964 | Mr. M. Ilahi | Amin Jute Baling Co. Ltd. |
| 1965 | Mr. Y. A. Bawany | Aesons Limited |
| 1966 | Mr. A. A. Khalon | The Pakbay Co. Ltd |
| 1967 | Mr. M. Ilahi | Amin Jute Baling Co. Ltd. |
| 1968 | Mr. M. Ilahi | Amin Jute Baling Co. Ltd. |
| 1969 | Mr. Rashid Ahmed | Sinclair Murray (Pakistan) Ltd |
| 1970 | Mr. Rashid Ahmed | Sinclair Murray (Pakistan) Ltd |
| 1971 | Mr. A. Qayyum | Pakistan River Steamers Ltd. |
| 1972 | Mr. Kamruddin Ahmed | Orr, Dignam & Co. |
| 1973 | Mr. Kamruddin Ahmed | Orr, Dignam & Co. |
| 1974 | Mr. Kamruddin Ahmed | Orr, Dignam & Co. |
| 1975 | Mr. F. K. Ghuznavi | ICI Bangladesh Ltd |
| 1976 | Mr. Rashid Ahmed | Sinclair Murray (Bangladesh) Ltd |
| 1977 | Mr. M. Anis Ud Dowla | Bangladesh Oxygen Ltd. |
| 1978 | Mr. M. Anis Ud Dowla | Bangladesh Oxygen Ltd. |
| 1979 | Mr. S. H. Kabir | Pfizer Laboratories (BD) Ltd |
| 1980 | Mr. Mushfeq-Us-Saleheen | International Finance and Investment Co. Ltd. |
| 1981 | Mr. M. Morshed Khan | Pacific Motors Limited |
| 1982 | Mr. M. Morshed Khan | Pacific Motors Limited |
| 1983 | Mr. Zeaul Huq | Orioxi Ltd. |
| 1984 | Mr. S. H. Kabir | Pfizer Laboratories (BD) Ltd |
| 1985 | Mr. M. R. Siddiqi | SIDCO Limited. |
| 1986 | Mr. M. R. Siddiqi | SIDCO Limited. |
| 1987 | Mr. Habibullah Khan | Ganges Motors Limited |
| 1988 | Mr. Habibullah Khan | Ganges Motors Limited |
| 1989 | Mr. Salman F. Rahman | Bangladesh Export Import Co. Ltd |
| 1990 | Mr. Syed Manzur Elahi | Apex Tannery Limited |
| 1991 | Mr. Syed Manzur Elahi | Apex Tannery Limited |
| 1992 | Mr. M. Morshed Khan | Pacific Motors Limited |
| 1993 | Mr. Latifur Rahman | Transcom Limited |
| 1994 | Mr. Latifur Rahman | Transcom Limited |
| 1995 | Mr. M. Anis Ud Dowla | Advanced Chemical Industries |
| 1996 | Mr. Samson H. Chowdhury | Square Pharmaceuticals Limited |
| 1997 | Mr. Samson H. Chowdhury | Square Pharmaceuticals Limited |
| 1998 | Mrs. Laila Rahman Kabir | Kedarpur Tea Company Ltd |
| 1999 | Mr. Mahbub Jamil | International Leasing and Financial Services Limited |
| 2000 | Mr. Latifur Rahman | Transcom Limited |
| 2001 | Mr. Latifur Rahman | Transcom Limited |
| 2002 | Mr. Tapan Chowdhury | Square Pharmaceuticals Limited |
| 2003 | Mr. Tapan Chowdhury | Square Pharmaceuticals Limited |
| 2004 | Mr. Kutubuddin Ahmed | Envoy Garments Limited |
| 2005 | Mr. Kutubuddin Ahmed | Envoy Garments Limited |
| 2006 | Mr. Latifur Rahman | Transcom Limited |
| 2007 | Mr. Latifur Rahman | Transcom Limited |
| 2008 | Mr. Latifur Rahman | Transcom Limited |
| 2009 | Mr. Abdul Hafiz Choudhury, FCA | Rahman Rahman Huq |
| 2010 | Mr. M. Anis Ud Dowla | Advanced Chemical Industries |
| 2011 | Maj. Gen Amjad Khan Chowdhury (Retd) | Agricultural Marketing Co. Ltd. |
| 2012 | Maj. Gen Amjad Khan Chowdhury (Retd) | Agricultural Marketing Co. Ltd. |
| 2013 | Ms. Rokia Afzal Rahman | Arlinks Limited. |
| 2014 | Ms. Rokia Afzal Rahman | Arlinks Limited. |
| 2015 | Mr. Syed Nasim Manzur | Apex Footwear Ltd. |
| 2016 | Mr. Syed Nasim Manzur | Apex Footwear Ltd. |
| 2017 | Ms. Nihad Kabir | Syed Ishtiaq Ahmed & Associates |
| 2018 | Ms. Nihad Kabir | Syed Ishtiaq Ahmed & Associates |
| 2019 | Ms. Nihad Kabir | Syed Ishtiaq Ahmed & Associates |
| 2020 | Ms. Nihad Kabir | Syed Ishtiaq Ahmed & Associates |